Wnt2 Regulates Progenitor Proliferation in the Developing Ventral Midbrain

Wnts are secreted, lipidated proteins that regulate multiple aspects of brain development, including dopaminergic neuron development. In this study, we perform the first purification and signaling analysis of Wnt2 and define the function of Wnt2 in ventral midbrain precursor cultures, as well as in...

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Hauptverfasser: Sousa, Kyle M., Villaescusa, J. Carlos, Cajanek, Lukas, Ondr, Jennifer K., Castelo-Branco, Goncalo, Hofstra, Wytske, Bryja, Vitezslav, Palmberg, Carina, Bergman, Tomas, Wainwright, Brandon, Lang, Richard A., Arenas, Ernest
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844173/
https://ncbi.nlm.nih.gov/pubmed/20018874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.079822
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