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Tiam1 Regulates the Wnt/Dvl/Rac1 Signaling Pathway and the Differentiation of Midbrain Dopaminergic Neurons

Understanding the mechanisms that drive the differentiation of dopaminergic (DA) neurons is crucial for successful development of novel therapies for Parkinson's disease, in which DA neurons progressively degenerate. However, the mechanisms underlying the differentiation-promoting effects of Wn...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Čajánek, Lukáš, Ganji, Ranjani Sri, Henriques-Oliveira, Catarina, Theofilopoulos, Spyridon, Koník, Peter, Bryja, Vítězslav, Arenas, Ernest
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536309/
https://ncbi.nlm.nih.gov/pubmed/23109420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00745-12
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