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Tiam1 Regulates the Wnt/Dvl/Rac1 Signaling Pathway and the Differentiation of Midbrain Dopaminergic Neurons

Understanding the mechanisms that drive the differentiation of dopaminergic (DA) neurons is crucial for successful development of novel therapies for Parkinson's disease, in which DA neurons progressively degenerate. However, the mechanisms underlying the differentiation-promoting effects of Wn...

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Библиографические подробности
Главные авторы: Čajánek, Lukáš, Ganji, Ranjani Sri, Henriques-Oliveira, Catarina, Theofilopoulos, Spyridon, Koník, Peter, Bryja, Vítězslav, Arenas, Ernest
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536309/
https://ncbi.nlm.nih.gov/pubmed/23109420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00745-12
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