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Tiam1 Regulates the Wnt/Dvl/Rac1 Signaling Pathway and the Differentiation of Midbrain Dopaminergic Neurons

Understanding the mechanisms that drive the differentiation of dopaminergic (DA) neurons is crucial for successful development of novel therapies for Parkinson's disease, in which DA neurons progressively degenerate. However, the mechanisms underlying the differentiation-promoting effects of Wn...

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Detalhes bibliográficos
Main Authors: Čajánek, Lukáš, Ganji, Ranjani Sri, Henriques-Oliveira, Catarina, Theofilopoulos, Spyridon, Koník, Peter, Bryja, Vítězslav, Arenas, Ernest
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536309/
https://ncbi.nlm.nih.gov/pubmed/23109420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00745-12
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