Wnt2 Regulates Progenitor Proliferation in the Developing Ventral Midbrain

Wnts are secreted, lipidated proteins that regulate multiple aspects of brain development, including dopaminergic neuron development. In this study, we perform the first purification and signaling analysis of Wnt2 and define the function of Wnt2 in ventral midbrain precursor cultures, as well as in...

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Detalles Bibliográficos
Main Authors: Sousa, Kyle M., Villaescusa, J. Carlos, Cajanek, Lukas, Ondr, Jennifer K., Castelo-Branco, Goncalo, Hofstra, Wytske, Bryja, Vitezslav, Palmberg, Carina, Bergman, Tomas, Wainwright, Brandon, Lang, Richard A., Arenas, Ernest
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Developmental Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844173/
https://ncbi.nlm.nih.gov/pubmed/20018874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.079822
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