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Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors

Degeneration of dopamine neurons in the midbrain causes symptoms of the movement disorder, Parkinson disease. Dopamine neurons are generated from proliferating progenitor cells localized in the embryonic ventral midbrain. However, it remains unclear for how long cells with dopamine progenitor charac...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Hedlund, Eva, Belnoue, Laure, Theofilopoulos, Spyridon, Salto, Carmen, Bye, Chris, Parish, Clare, Deng, Qiaolin, Kadkhodaei, Banafsheh, Ericson, Johan, Arenas, Ernest, Perlmann, Thomas, Simon, András
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887985/
https://ncbi.nlm.nih.gov/pubmed/27246266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26448
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