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Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons
The LIM-homeodomain transcription factors Lmx1a and Lmx1b play critical roles during the development of midbrain dopaminergic progenitors, but their functions in the adult brain remain poorly understood. We show here that sustained expression of Lmx1a and Lmx1b is required for the survival of adult...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4968767/ https://ncbi.nlm.nih.gov/pubmed/27407143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520387113 |
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