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Engineering subunit association of multisubunit proteins: A dimeric streptavidin

A dimeric streptavidin has been designed by molecular modeling using effective binding free energy calculations that decompose the binding free energy into electrostatic, desolvation, and side chain entropy loss terms. A histidine-127 → aspartic acid (H127D) mutation was sufficient to introduce elec...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Sano, Takeshi, Vajda, Sandor, Smith, Cassandra L., Cantor, Charles R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences of the USA 1997
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC21018/
https://ncbi.nlm.nih.gov/pubmed/9177186
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