A new approach for containment of microorganisms: Dual control of streptavidin expression by antisense RNA and the T7 transcription system

The use of microorganisms in the open environment would be of less concern if they were endowed with programmed self-destruction mechanisms. Here, we propose a new genetic design to increase the effectiveness of cell suicide systems. It ensures very tight control of the derepression of cell death by...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Szafranski, Przemyslaw, Mello, Charlene M., Sano, Takeshi, Smith, Cassandra L., Kaplan, David L., Cantor, Charles R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19743/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1059
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