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A new approach for containment of microorganisms: Dual control of streptavidin expression by antisense RNA and the T7 transcription system

The use of microorganisms in the open environment would be of less concern if they were endowed with programmed self-destruction mechanisms. Here, we propose a new genetic design to increase the effectiveness of cell suicide systems. It ensures very tight control of the derepression of cell death by...

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Main Authors: Szafranski, Przemyslaw, Mello, Charlene M., Sano, Takeshi, Smith, Cassandra L., Kaplan, David L., Cantor, Charles R.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC19743/
https://ncbi.nlm.nih.gov/pubmed/9037005
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