A structural snapshot of an intermediate on the streptavidin–biotin dissociation pathway
It is currently unclear whether small molecules dissociate from a protein binding site along a defined pathway or through a collection of dissociation pathways. We report herein a joint crystallographic, computational, and biophysical study that suggests the Asp-128 → Ala (D128A) streptavidin mutant...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17525/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411884/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.15.8384 |
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