Peripheral Disruption of the Grb10 Gene Enhances Insulin Signaling and Sensitivity In Vivo

Grb10 is a pleckstrin homology and Src homology 2 domain-containing protein that interacts with a number of phosphorylated receptor tyrosine kinases, including the insulin receptor. In mice, Grb10 gene expression is imprinted with maternal expression in all tissues except the brain. While the intera...

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Autori principali: Wang, Lixin, Balas, Bogdan, Christ-Roberts, Christine Y., Kim, Ryang Yeo, Ramos, Fresnida J., Kikani, Chintan K., Li, Cuiling, Deng, Chuxia, Reyna, Sara, Musi, Nicolas, Dong, Lily Q., DeFronzo, Ralph A., Liu, Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099625/
https://ncbi.nlm.nih.gov/pubmed/17620412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00679-07
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