Genetic Disruption of SOD1 Gene Causes Glucose Intolerance and Impairs β-Cell Function

Oxidative stress has been associated with insulin resistance and type 2 diabetes. However, it is not clear whether oxidative damage is a cause or a consequence of the metabolic abnormalities present in diabetic subjects. The goal of this study was to determine whether inducing oxidative damage throu...

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Main Authors: Muscogiuri, Giovanna, Salmon, Adam B., Aguayo-Mazzucato, Cristina, Li, Mengyao, Balas, Bogdan, Guardado-Mendoza, Rodolfo, Giaccari, Andrea, Reddick, Robert L., Reyna, Sara M., Weir, Gordon, DeFronzo, Ralph A., Van Remmen, Holly, Musi, Nicolas
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837066/
https://ncbi.nlm.nih.gov/pubmed/24009256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0314
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