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Degradation of C-terminal Truncated αA-crystallins by the Ubiquitin–Proteasome Pathway
PURPOSE: Calpain-mediated C-terminal cleavage of αA-crystallins occurs during aging and cataractogenesis. The objective of the present study was to explore the role of the ubiquitin-proteasome pathway (UPP) in degrading C-terminal truncated αA-crystallins. METHODS: Recombinant wild-type (wt) αA-crys...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2098745/ https://ncbi.nlm.nih.gov/pubmed/17724207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-0196 |
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