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Glutathiolation Enhances the Degradation of γC-crystallin in Lens and Reticulocyte Lysates, Partially via the Ubiquitin–Proteasome Pathway

PURPOSE: S-glutathiolated proteins are formed in the lens during aging and cataractogenesis. The objective of this work was to explore the role of the ubiquitin–proteasome pathway in eliminating S-glutathiolated γC-crystallin. METHODS: Recombinant human γC-crystallin was mixed with various concentra...

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Библиографические подробности
Главные авторы: Zetterberg, Madeleine, Zhang, Xinyu, Taylor, Allen, Liu, Bingfen, Liang, Jack J., Shang, Fu
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117893/
https://ncbi.nlm.nih.gov/pubmed/16877417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-1664
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