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Glutathiolation Enhances the Degradation of γC-crystallin in Lens and Reticulocyte Lysates, Partially via the Ubiquitin–Proteasome Pathway
PURPOSE: S-glutathiolated proteins are formed in the lens during aging and cataractogenesis. The objective of this work was to explore the role of the ubiquitin–proteasome pathway in eliminating S-glutathiolated γC-crystallin. METHODS: Recombinant human γC-crystallin was mixed with various concentra...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2117893/ https://ncbi.nlm.nih.gov/pubmed/16877417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-1664 |
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