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The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones
Accumulation of damaged proteins is causally related to many age-related diseases. The ubiquitin-proteasome pathway (UPP) plays a role in selective degradation of damaged proteins, whereas molecular chaperones, such as heat shock proteins, are involved in refolding denatured proteins. This work demo...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2100384/ https://ncbi.nlm.nih.gov/pubmed/16469848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.05-5080fje |
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