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The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones

Accumulation of damaged proteins is causally related to many age-related diseases. The ubiquitin-proteasome pathway (UPP) plays a role in selective degradation of damaged proteins, whereas molecular chaperones, such as heat shock proteins, are involved in refolding denatured proteins. This work demo...

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Bibliografski detalji
Glavni autori: Marques, Carla, Guo, Weimin, Pereira, Paulo, Taylor, Allen, Patterson, Cam, Evans, Paul C., Shang, Fu
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2100384/
https://ncbi.nlm.nih.gov/pubmed/16469848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.05-5080fje
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