A single point mutation results in a constitutively activated and feedback-resistant chorismate mutase of Saccharomyces cerevisiae.

The Saccharomyces cerevisiae ARO7 gene product chorismate mutase, a single-branch-point enzyme in the aromatic amino acid biosynthetic pathway, is activated by tryptophan and subject to feedback inhibition by tyrosine. The ARO7 gene was cloned on a 2.05-kilobase EcoRI fragment. Northern (RNA) analys...

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Autores principales: Schmidheini, T, Sperisen, P, Paravicini, G, Hütter, R, Braus, G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC209737/
https://ncbi.nlm.nih.gov/pubmed/2646272
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