A single point mutation results in a constitutively activated and feedback-resistant chorismate mutase of Saccharomyces cerevisiae.

The Saccharomyces cerevisiae ARO7 gene product chorismate mutase, a single-branch-point enzyme in the aromatic amino acid biosynthetic pathway, is activated by tryptophan and subject to feedback inhibition by tyrosine. The ARO7 gene was cloned on a 2.05-kilobase EcoRI fragment. Northern (RNA) analys...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Schmidheini, T, Sperisen, P, Paravicini, G, Hütter, R, Braus, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209737/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2646272/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.171.3.1245-1253.1989
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