Reduced activity of 11β-hydroxysteroid dehydrogenase in patients with cholestasis
Enhanced renal sodium retention and potassium loss in patients with cirrhosis is due to activation of mineralocorticoid receptors (MRs). Increased aldosterone concentrations, however, do not entirely explain the activation of MR in cirrhosis. Here, we hypothesize that cortisol activates MRs in patie...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209437/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11696574/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI12745 |
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