Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities

Creating endonucleases with novel sequence specificities provides more possibilities to manipulate DNA. We have created a chimeric endonuclease (CH-endonuclease) consisting of the DNA cleavage domain of BmrI restriction endonuclease and C.BclI, a controller protein of the BclI restriction-modificati...

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Bibliographic Details
Main Authors: Chan, Siu-hong, Bao, Yongming, Ciszak, Ewa, Laget, Sophie, Xu, Shuang-yong
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094064/
https://ncbi.nlm.nih.gov/pubmed/17855396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm665
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