Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie

Transmissible spongiform encephalopathies display long incubation periods at the beginning of which the titer of infectious agents (prions) increases in peripheral lymphoid organs. This “replication” leads to a progressive invasion of the CNS. Follicular dendritic cells appear to support prion repli...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Aucouturier, Pierre, Geissmann, Frédéric, Damotte, Diane, Saborio, Gabriela P., Meeker, Harry C., Kascsak, Regina, Kascsak, Richard, Carp, Richard I., Wisniewski, Thomas
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC209385/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11544275/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI13155
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