Systemic IFN-β gene therapy results in long-term survival in mice with established colorectal liver metastases

Most patients succumbing to colorectal cancer fail with liver-predominant metastases. To make a clinical impact in this disease, a systemic or whole-liver therapy may be required, whereas most cancer gene therapy approaches are limited in their ability to treat beyond local disease. As a preclinical...

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Detalhes bibliográficos
Main Authors: Tada, Hiroomi, Maron, David J., Choi, Eugene A., Barsoum, James, Lei, Hanqin, Xie, Qing, Liu, Wenbiao, Ellis, Lee, Moscioni, A. David, Tazelaar, John, Fawell, Stephen, Qin, Xiao, Propert, Kathleen J., Davis, Alan, Fraker, Douglas L., Wilson, James M., Spitz, Francis R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209332/
https://ncbi.nlm.nih.gov/pubmed/11435460
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