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Interferon-β gene therapy inhibits tumor formation and causes regression of established tumors in immune-deficient mice

Despite the potential of type 1 interferons (IFNs) for the treatment of cancer, clinical experience with IFN protein therapy of solid tumors has been disappointing. IFN-β has potent antiproliferative activity against most human tumor cells in vitro in addition to its known immunomodulatory activitie...

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Detalhes bibliográficos
Main Authors: Qin, Xiao-Qiang, Tao, Nianjun, Dergay, Amie, Moy, Pamela, Fawell, Stephen, Davis, Alan, Wilson, James M., Barsoum, James
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24387/
https://ncbi.nlm.nih.gov/pubmed/9826714
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