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Inactivation of interferon receptor promotes the establishment of immune privileged tumor microenvironment
Refractoriness of solid tumors including colorectal cancers (CRC) to immunotherapies is attributed to the immunosuppressive tumor microenvironment that protects malignant cells from cytotoxic T lymphocytes (CTL). We found that downregulation of the type I interferon receptor chain IFNAR1 occurs in h...
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Publicado no: | Cancer Cell |
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Main Authors: | , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5313042/ https://ncbi.nlm.nih.gov/pubmed/28196594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.01.004 |
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