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Impaired IL-18 processing protects caspase-1–deficient mice from ischemic acute renal failure
We sought to determine whether mice deficient in the proinflammatory caspase-1, which cleaves precursors of IL-1β and IL-18, were protected against ischemic acute renal failure (ARF). Caspase-1(–/–) mice developed less ischemic ARF as judged by renal function and renal histology. These animals had s...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC209282/ https://ncbi.nlm.nih.gov/pubmed/11342578 |
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