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Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy
This study was undertaken to investigate the role of mouse double minute 2 (MDM2) oncogene in prostate cancer growth and the potential of MDM2 as a target for prostate cancer therapy. An antisense anti-human–MDM2 mixed-backbone oligonucleotide was tested in human prostate cancer models with various...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC208810/ https://ncbi.nlm.nih.gov/pubmed/13130078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1934692100 |
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