Negative selection imparts peptide specificity to the mature T cell repertoire
The T cell αβ receptor (TCR) recognizes foreign peptide antigens bound to proteins encoded in the MHC. The MHC portion of this complex contributes much to the footprint of the TCR on the ligand, yet T cells are usually very specific for individual foreign peptides. Here, we show that the development...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2003
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14504410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1934636100 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|