SOS-dependent replication past a single trans-syn T-T cyclobutane dimer gives a different mutation spectrum and increased error rate compared with replication past this lesion in uninduced cells.

We have transfected SOS-induced and uninduced cells of a uvrA6 strain of Escherichia coli with single-stranded M13mp7-based vectors that carried a single trans-syn T-T cyclobutane dimer at a unique site. Unlike constructs carrying the cis-syn isomer of this lesion, these vectors could be replicated...

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Detalhes bibliográficos
Main Authors: Banerjee, S K, Borden, A, Christensen, R B, LeClerc, J E, Lawrence, C W
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC208710/
https://ncbi.nlm.nih.gov/pubmed/2180917
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