SOS-dependent replication past a single trans-syn T-T cyclobutane dimer gives a different mutation spectrum and increased error rate compared with replication past this lesion in uninduced cells.

We have transfected SOS-induced and uninduced cells of a uvrA6 strain of Escherichia coli with single-stranded M13mp7-based vectors that carried a single trans-syn T-T cyclobutane dimer at a unique site. Unlike constructs carrying the cis-syn isomer of this lesion, these vectors could be replicated...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Banerjee, S K, Borden, A, Christensen, R B, LeClerc, J E, Lawrence, C W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208710/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2180917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.4.2105-2112.1990
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!