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SOS-dependent replication past a single trans-syn T-T cyclobutane dimer gives a different mutation spectrum and increased error rate compared with replication past this lesion in uninduced cells.

We have transfected SOS-induced and uninduced cells of a uvrA6 strain of Escherichia coli with single-stranded M13mp7-based vectors that carried a single trans-syn T-T cyclobutane dimer at a unique site. Unlike constructs carrying the cis-syn isomer of this lesion, these vectors could be replicated...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Principais autores: Banerjee, S K, Borden, A, Christensen, R B, LeClerc, J E, Lawrence, C W
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC208710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2180917/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.4.2105-2112.1990
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