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In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DM

The independent influences of invariant chain (Ii) and HLA-DM molecules on the array of naturally processed peptides displayed by HLA-DR molecules were studied using transfected cell lines. The absence of Ii led to an altered set of HLA-DR-bound peptides as judged by the discriminating responses of...

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Autori principali: Lightstone, Liz, Hargreaves, Roseanna, Bobek, Gabriele, Peterson, Mary, Aichinger, Gerald, Lombardi, Giovanna, Lechler, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC20855/
https://ncbi.nlm.nih.gov/pubmed/9159149
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