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Direct Observation of Active Protein Folding Using Lock-in Force Spectroscopy

Direct observation of the folding of a single polypeptide chain can provide important information about the thermodynamic states populated along its folding pathway. In this study, we present a lock-in force-spectroscopy technique that improves resolution of atomic-force microscopy force spectroscop...

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Détails bibliographiques
Auteurs principaux: Schlierf, Michael, Berkemeier, Felix, Rief, Matthias
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084248/
https://ncbi.nlm.nih.gov/pubmed/17704164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.114397
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