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Molecular Dynamics Simulations of Two Tandem Octarepeats from the Mammalian Prion Protein: Fully Cu(2+)-bound and Metal-Free Forms
Molecular dynamics simulations have been conducted on a model fragment (Ac-PHGGGWGQPHGGGW-NH(2)) of the prion protein octarepeat domain, both in the Cu(2+)-bound and metal-free forms. The copper-bound models are based on the consensus structure of the core Cu(2+)-binding site of an individual octare...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Biophysical Society
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084230/ https://ncbi.nlm.nih.gov/pubmed/17704169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.109512 |
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