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New Insights into Metal Interactions with the Prion Protein: EXAFS Analysis and Structure Calculations of Copper Binding to a Single Octarepeat from the Prion Protein

Copper coordination to the prion protein (PrP) has garnered considerable interest for almost 20 years, due in part to the possibility that this interaction may be part of the normal function of PrP. The most characterized form of copper binding to PrP has been Cu(2+) interaction with the conserved t...

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Detalhes bibliográficos
Main Authors: McDonald, Alex, Pushie, M. Jake, Millhauser, Glenn L., George, Graham N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890359/
https://ncbi.nlm.nih.gov/pubmed/24102071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp408239h
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