The Role of the Octarepeat Region in Neuroprotective Function of the Cellular Prion Protein

Structural alterations of the cellular prion protein (PrP(C)) seem to be the core of the pathogenesis of prion diseases. However, the physiological function of PrP(C )remains an enigma. Cell culture experiments have indicated that PrP(C) and in particular its N‐terminal octarepeat region together wi...

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Detalhes bibliográficos
Main Authors: Mitteregger, Gerda, Vosko, Milan, Krebs, Bjarne, Xiang, Wei, Kohlmannsperger, Veronika, Nölting, Svenja, Hamann, Gerhard F., Kretzschmar, Hans A.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859984/
https://ncbi.nlm.nih.gov/pubmed/17388948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2007.00061.x
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