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mTOR is the Rapamycin-Sensitive Kinase that Confers Mechanically-Induced Phosphorylation of the Hydrophobic Motif Site Thr(389) in p70(S6k)
Mechanical stretch induces phosphorylation of the hydrophobic motif site Thr389 in p70(S6k) through a rapamycin-sensitive (RS) pathway that involves a unique PI3K-independent mechanism. Rapamycin is considered to be a highly specific inhibitor of the protein kinase mTOR; however, mTOR is also consid...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084087/ https://ncbi.nlm.nih.gov/pubmed/17825298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.08.045 |
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