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Diffusion control in an elementary protein folding reaction

The cold-shock protein CspB (from Bacillus subtilis), a very small protein of 67 residues, folds extremely fast in a reversible N ⇋ U two-state reaction. Both unfolding and refolding are strongly decelerated when the viscosity of the solvent is increased by adding ethylene glycol or sucrose. The fol...

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Bibliografiske detaljer
Main Authors: Jacob, Maik, Schindler, Thomas, Balbach, Jochen, Schmid, Franz X.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20828/
https://ncbi.nlm.nih.gov/pubmed/9159122
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