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Structure-function analysis of the retinoblastoma tumor suppressor protein – is the whole a sum of its parts?

Biochemical analysis of the retinoblastoma protein's function has received considerable attention since it was cloned just over 20 years ago. During this time pRB has emerged as a key regulator of the cell division cycle and its ability to block proliferation is disrupted in the vast majority o...

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Bibliographic Details
Main Author: Dick, Frederick A
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2082274/
https://ncbi.nlm.nih.gov/pubmed/17854503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-2-26
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