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Posttranslational Modifications of the Retinoblastoma Tumor Suppressor Protein as Determinants of Function
The retinoblastoma tumor suppressor protein (pRB) plays an integral role in G(1)-S checkpoint control and consequently is a frequent target for inactivation in cancer. The RB protein can function as an adaptor, nucleating components such as E2Fs and chromatin regulating enzymes into the same complex...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publications
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3636757/ https://ncbi.nlm.nih.gov/pubmed/23634251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912473305 |
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