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Conditional haploinsufficiency of the retinoblastoma tumor suppressor gene
Recent work demonstrates that retention of a single functional retinoblastoma susceptibility (RB1) allele is insufficient to maintain genome stability. Haploinsufficiency of RB1 accelerates cancer pathogenesis in concert with inactivation of tumor protein p53. Collectively, multiple lines of evidenc...
Shranjeno v:
| izdano v: | Mol Cell Oncol |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905237/ https://ncbi.nlm.nih.gov/pubmed/27308386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.968069 |
| Oznake: |
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