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Early embryonic lethality caused by targeted disruption of the mouse selenocysteine tRNA gene (Trsp)
Selenoprotein biosynthesis is mediated by tRNA(Sec), which inserts selenocysteine at UGA codons in a complex, context-specific manner. This opal suppressor serves in the conversion of serine to selenocysteine as well. The mouse tRNA(Sec) gene (Trsp) maps to a proximal segment of chromosome 7. We con...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences of the USA
1997
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20812/ https://ncbi.nlm.nih.gov/pubmed/9159106 |
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