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Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes

Double-stranded RNA-binding proteins (dsRBPs), such as R2D2 and Loquacious (Loqs), function in tandem with Dicer (Dcr) enzymes in RNA interference (RNAi). In Drosophila, Dcr-1/Loqs and Dcr-2/R2D2 complexes generate microRNAs (miRNAs) and small interfering RNAs (siRNAs), respectively. Although R2D2 d...

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Detalhes bibliográficos
Main Authors: Liu, Xiang, Park, Joseph K., Jiang, Feng, Liu, Ying, McKearin, Dennis, Liu, Qinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080612/
https://ncbi.nlm.nih.gov/pubmed/17928574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.723707
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