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Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes
Double-stranded RNA-binding proteins (dsRBPs), such as R2D2 and Loquacious (Loqs), function in tandem with Dicer (Dcr) enzymes in RNA interference (RNAi). In Drosophila, Dcr-1/Loqs and Dcr-2/R2D2 complexes generate microRNAs (miRNAs) and small interfering RNAs (siRNAs), respectively. Although R2D2 d...
में बचाया:
मुख्य लेखकों: | , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Cold Spring Harbor Laboratory Press
2007
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080612/ https://ncbi.nlm.nih.gov/pubmed/17928574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.723707 |
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