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Stimulation of picornavirus replication by the poly(A) tail in a cell-free extract is largely independent of the poly(A) binding protein (PABP)

Picornavirus infectivity is dependent on the RNA poly(A) tail, which binds the poly(A) binding protein (PABP). PABP was reported to stimulate viral translation and RNA synthesis. Here, we studied encephalomyocarditis virus (EMCV) and poliovirus (PV) genome expression in Krebs-2 and HeLa cell-free ex...

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Detaylı Bibliyografya
Asıl Yazarlar: Svitkin, Yuri V., Costa-Mattioli, Mauro, Herdy, Barbara, Perreault, Sandra, Sonenberg, Nahum
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080607/
https://ncbi.nlm.nih.gov/pubmed/17942745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.606407
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