Stimulation of picornavirus replication by the poly(A) tail in a cell-free extract is largely independent of the poly(A) binding protein (PABP)

Picornavirus infectivity is dependent on the RNA poly(A) tail, which binds the poly(A) binding protein (PABP). PABP was reported to stimulate viral translation and RNA synthesis. Here, we studied encephalomyocarditis virus (EMCV) and poliovirus (PV) genome expression in Krebs-2 and HeLa cell-free ex...

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Bibliografiska uppgifter
Huvudupphovsmän: Svitkin, Yuri V., Costa-Mattioli, Mauro, Herdy, Barbara, Perreault, Sandra, Sonenberg, Nahum
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080607/
https://ncbi.nlm.nih.gov/pubmed/17942745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.606407
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