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Wild-type is the optimal sequence of the HDV ribozyme under cotranscriptional conditions
RNA viruses are responsible for a variety of human diseases, and the pathogenicity of RNA viruses is often attributed to a high rate of mutation. Self-cleavage activity of the wild-type hepatitis delta virus (HDV) ribozyme as measured in standard divalent ion renaturation assays is biphasic and most...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080589/ https://ncbi.nlm.nih.gov/pubmed/17956974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.778107 |
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