Structural basis for the autoinhibition of Focal Adhesion Kinase

Appropriate tyrosine kinase signaling depends on coordinated sequential coupling of protein-protein interactions with catalytic activation. Focal adhesion kinase (FAK) integrates signals from integrin and growth factor receptors to regulate cellular responses including cell adhesion, migration and s...

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Bibliografiske detaljer
Main Authors: Lietha, Daniel, Cai, Xinming, Ceccarelli, Derek F.J., Li, Yiqun, Schaller, Michael D., Eck, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077847/
https://ncbi.nlm.nih.gov/pubmed/17574028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.05.041
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