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Absence of regulatory T-cell control of T(H)1 and T(H)17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease
Graft-versus-host disease (GVHD) remains the major complication after allogeneic bone marrow transplantation (BMT). The process whereby acute GVHD mediated by alloreactive donor T cells transitions into chronic GVHD, which is characterized by prominent features of auto-immunity, has long been unreso...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2007
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2077325/ https://ncbi.nlm.nih.gov/pubmed/17693581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-091074 |
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