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Homeostatic expansion and repertoire regeneration of donor T cells during graft versus host disease is constrained by the host environment

Graft versus host disease (GVHD) typically results in impaired T-cell reconstitution characterized by lymphopenia and repertoire skewing. One of the major causes of inadequate T-cell reconstitution is that T-cell survival and expansion in the periphery are impaired. In this report, we have performed...

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Detalhes bibliográficos
Main Authors: Gorski, Jack, Chen, Xiao, Gendelman, Mariya, Yassai, Maryam, Krueger, Ashley, Tivol, Elizabeth, Logan, Brent, Komorowski, Richard, Vodanovic-Jankovic, Sanja, Drobyski, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890817/
https://ncbi.nlm.nih.gov/pubmed/17347406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-12-061713
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