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NF-κB as a target for the prevention of graft-versus-host disease: comparative efficacy of bortezomib and PS-1145
NF-κB is a transcription factor that controls the expression of a number of genes important for mediating immune and inflammatory responses. In this study, we examined whether bortezomib and PS-1145, each of which inhibits NF-κB, could protect mice from lethal graft-versus-host disease (GVHD), which...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society of Hematology
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895627/ https://ncbi.nlm.nih.gov/pubmed/16174760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-1820 |
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