Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1

Gene expression profiling of acute myeloid leukemia (AML) allows the discovery of previously unrecognized molecular entities. Here, we identified a specific subgroup of AML, defined by an expression profile resembling that of AMLs with mutations in the myeloid transcription factor CCAAT/enhancer-bin...

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Autori principali: Wouters, Bas J., Jordà, Meritxell Alberich, Keeshan, Karen, Louwers, Irene, Erpelinck-Verschueren, Claudia A. J., Tielemans, Dennis, Langerak, Anton W., He, Yiping, Yashiro-Ohtani, Yumi, Zhang, Pu, Hetherington, Christopher J., Verhaak, Roel G. W., Valk, Peter J. M., Löwenberg, Bob, Tenen, Daniel G., Pear, Warren S., Delwel, Ruud
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2007
Soggetti:
Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077318/
https://ncbi.nlm.nih.gov/pubmed/17671232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-02-073486
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