Human Artificial Chromosomes with Alpha Satellite-Based De Novo Centromeres Show Increased Frequency of Nondisjunction and Anaphase Lag
Human artificial chromosomes have been used to model requirements for human chromosome segregation and to explore the nature of sequences competent for centromere function. Normal human centromeres require specialized chromatin that consists of alpha satellite DNA complexed with epigenetically modif...
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| Vydáno v: | Mol Cell Biol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC207596/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14560014/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.21.7689-7697.2003 |
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